I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. Wear sunscreen (at least SPF 15) every day, wear sunglasses and long sleeves/pants to protect your skin. I took nausea tabs even when I wasn't nausaus, but it made little difference. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. For now, just concentrate on YOU! I have severe bloating which is so uncomfortable its almost painful. You may also need to take your temperature at home during your treatment to stay on top of fevers. You should feel a lot better in about a week's time. So she then got a lumpectomy. Platelets help your blood clot, so when the count is low you are at a higher risk of bleeding. Some common Taxotere side effects include: vomiting nausea loss of appetite constipation diarrhea injection site reactions (redness, pain, or swelling) You should let your doctor or nurse know if you experience any shortness of breath, difficulty breathing, or pain in your chest. Write down how you feel each day, it's surprising how this can reduce distress, upset and even ease SE's a little. So far I have been ok on the 2nd cycle just starting to feel the side effects kicking in this evening . I've had 2, 3rd one tomorrow. But I am in good health and loving life. But as I say.. We're now closer to the end.. 2 more to go.. Then an operation for me And immunotherapy for a year but chemo and op are the big ones to get over.. You'll get through it.. And there is life after chemo. Saying goodbye to our 8th graders and saying" Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. Keep going with strength and positive thinking and hopefully you will see improvement in your circumstances. Taxotere Chemo: April 29 2010 May 20 2010 June 10 2010 July 1 2010. Brady appears to be expanding his brand rapidly in 2023. Basically I'm at my lowest and need positive boost. So would recommend this. My husband has booked a cottage break in July to hopefully celebrate the end of chemo before my surgery. Taxotere injections can cause serious and life-threatening fluid retention(edema). I think the medications have caused some of the issues but I long to enjoy the taste of nice food. I'll be starting this Thursday and have 10 steroids to take Wednesday night and then whatever they give me as pre-meds. Call your oncology care team if you are unable to keep fluids down for more than 12 hours or if you feel lightheaded or dizzy at any time. I was better prepared for the following two though. keep up the good work you have been doing and are still doing. I have been given so many tablets with this cycle which need to be taken with food but find eating almost impossible due to chemo mouth explosion of thrush despite being on medication. for use in the treatment of prostate cancer in the year 2004. Your story kinda reads similar to my wife's when she was on Docetaxel. Hope you are well now too. It really helped me that there was a gap between the two sets of chemo cycles, gave me a chance to recover a bit from the taxotere before starting the treatments again. This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! X, Reading all the comments, many of us have been through the mill with this 4th treatment. I spent a week in hospital after the 3rd Taxotere + radiotherapy. Been told its best to as it helps the operation be morebsuccessful. Signs of a reaction can include: shortness of breath or difficulty breathing, swelling of the face, lips, tongue or throat, trouble swallowing, chest pain, rash, flushing, hives or itching or a decrease in blood pressure. Everything tasted like cardboard, which sucked because I love to eat. And pineapple sounds a good idea too! Your nurse will check you for signs of a reaction during your treatment. Thanks everyone for your messages of support. Found the freeze gell hit the joint areas better and gave relief. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. Days 4 and 5 were the hardest: nausea or just energy, emotions. I haven't been able to do anything. They have said I don't need to have a scan which I have found strange as I need the reassurance that all is okay and it hasn't gone anywhere else. For cycle 2 I used a great mouthwash - Difflam and have had no sore mouth problems since. Its often very difficult to treat edema caused by cancer and chemotherapy. I can smell but can't taste anything! July 16, 2018. Epiphora One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. The content on this site is for informational purposes only. The Herceptin I will take until December 2013. Know that you are two thirds of the way there. It is so much easier than the taxotere, virtually no side effects at all. How Docetaxel Is Given: Docetaxel is given through a vein (intravenously, IV) There is no pill form of docetaxel ; Premedication with a corticosteroid pill starting a day prior to docetaxel infusion for 3 days is given to reduce the severity of fluid retention and allergic reactions. Most people notice that their neuropathy gets better 2 to 4 months after chemotherapy, but it can take up to 1 year to fully go away. These symptoms can last for several months or longer after treatment ends. Thank you for the support, hope you are doing well. I was diagnosed in Feb 2013 and had a rt mastectomy op in March. Even if it is to moan. Plan times to rest during the day and conserve energy for more important activities. ).He was also encouraged to leave the bedroom to night-time even if it meant setting up a 'day bed' downstairs (he managed with using our sun lounger indoors which gave better support than the armchair and enabled him to just drop off any time he felt like it.) Taxotere is one of many breast cancer chemotherapy drugs. I would have Gemcitabine on week one. APAP vs. CPAP: Whats the Best Machine for Sleep Apnea? It was neoadjuvant chemotherapy, including Taxanes (Taxotere), Carboplatin, and Trastuzumab (Herceptin). This hair loss can be all body hair, including pubic, underarm, legs/arms, eyelashes, and nose hairs. Stick with it. That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! Researchers spent YEARS finding chemotherapy compounds that could attack prostate cancer cells. After this drug I could only eat about three things, dry crispbreads, toast and marmite and mandarin oranges - I lived almost exclusively on mandarins because everything else tasted disgusting. Taxotere is a mitotic inhibitor that interferes with your bodys cell division process. Paracetamol Ibuprofen/codiene didn't work. While it sounds harmless enough, constantly tearing eyes can cause other health issues. Not able to advise, but sending loads of hugs to get you through this traumatic part of your journey xxxxxxxx, You haven't gone wrong Dolbycat, as you said it effects everyone differently. I had my first Taxotere on Monday and am not coping at all. 01-06-2015 02:21. Remember your hair helps keep you warm in cold weather, so a hat is particularly important in cold weather or to protect you from the sun. If you experience nausea, lack of appetite, or other eating problems, discuss solutions with your doctor or nurse navigator. Differences in clearance for the two PRINT particles suggest that shape plays a role in reducing clearance by the MPS and enhancing tumor delivery. Take care. Taxol/Taxotere and Cytoxan (TC) therapy is one of the most common types of chemotherapy given to women with early-stage breast cancer. I was so tired, and I wasnt expecting that level of fatigue. HI Multitasker! You may have some of the above symptoms or you may not. My kids are 10 and 5. You should not drive after the infusion until you know how it will affect you. Avoid drinking alcohol on the day of your Taxotere injection. Include fiber in your diet (fruits and vegetables), drink 8-10 glasses of non-alcoholic fluids a day, and keep active. Take care. The most common side effect in day-to-day life is fatigue. I often feel like it's too much and want to give in. Days 1,8: Gemcitabine 900mg/m 2 IV at a rate of 10mg/m 2 /minute, followed by: Day 8: Docetaxel 75-100mg/m 2 IV over 1 hour. If you do not have a bowel movement for 2-3 days, you should contact your healthcare team for suggestions to relieve constipation. Taxol once every 3 weeks: 86.5% Taxotere once every 3 weeks: 87.3% Taxotere once a week: 86.2% Some doctors have wondered whether a taxane has benefits for women diagnosed with hormone-receptor-positive breast cancer. At least with experiencing this cycle we will be more prepared. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. I never threw up really, but I had underlying nausea all the time. MYTH #6: I'll permanently lose all my hair after chemo. nausea and vomiting. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. In some people, the symptoms slowly resolve after the medication is stopped, but for some, it never goes away completely. I have just had 4 cycles of FEC and other than the 3rd one, coped OK and carried on working a combination of at home and in work on my good week. We are all stronger than we think and even stronger than we give ourselves credit for! Many women who receive taxane -based chemotherapy to treat breast cancer experience long-term peripheral neuropathy, according to follow-up data from a large clinical trial. Your labs will be closely monitored prior to each dose of docetaxel and the dose may be decreased or held if your liver function is not normal. Common side effects of Tax are bone aches and pains, sore mouth/mouth ulcers, oral thrush, loss of taste. The Docetaxel/Taxotere is the drug causing this nasty side effect. Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . Stay strong honey xxxxxxxxxxx, Thank you Lainey66, I will give Kin gingival a try as I feel I am in a vicious circle of mouth problems making eating difficult and tablets which need to be taken with food. This medication can cause severe side effects if given to a patient whose liver function is abnormal. Liked the clearer head but found days 3 to 6 the worst when ankles, knees or hips gave way. Today is the first day of actually feeling better after first cycle of Docetaxel, I am going to enjoy this last week before the next cycle of chemo starts. Hopefully the extra meds your gp has prescribed will manage the thrush. Avoid mouthwashes that contain alcohol. Gone too far now to stop just need to finish the course. TAXOTERE was first approved for the F.D.A. And yes, for me at least, it is cumulative and is a bit worse each cycle. I have a good support system at home who do just about everything as I have been bed or sofa bound for the last 10 days with just small walks around the house to keep the circulation going. (2013) demonstrated that nano-formulation improved plasma PK and tumor delivery of Doc compared to the unprocessed Doc. Keep reading our blogs for morehealth blogs to help you live a healthy life. Docetaxel can cause your body to hold too much fluid, which can be a serious side effect. Docetaxel can pass into body fluids (urine, feces, vomit). I have weaned myself off the Co-Codamol as I don't want to rely on it and the bone aches have reduced considerably now. I have lost ALL taste buds. Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. Itis designed to target malignant cancer cells in your body. For your mouth get som kingingical mouth wash and rinse with salt water every hour or so. Then I will start on radiotherapy. If your mouth becomes dry, eat moist foods, drink plenty of fluids (6-8 glasses), and suck on sugarless hard candy. An absolute pleasure to have helped. Health Advice: What Is A CPAP Machine And How Does It Work? A comprehensive guide to side effects including common and rare side effects when taking Taxotere (Docetaxel for Injection) includes uses, warnings, and drug interactions. While we were driving home - it's a nice, sunny, fairly warm day - Moopy observed that getting out was a reminder of what our life will be like again. A week later and I still can't get out of bed! So always stay in touch with the team.. Im out now on antibiotics.. It causes numbness or a tingling feeling in the hands and/or feet, often in the pattern of a stocking or glove. I have had problems with temperaturechilly and drafts set off cough and shivering, warm and cosy sweating. . I mentioned this thread to her - the common wisdom that the first is the worst because of the uncertainty and the rest is more of the same, only more so. Last injection today. Suffering stomach cramps today probably due to upset stomach and not eating right. with 5 mg prednisone twice a day continuously (2.3) GC: 75 mg/m 2followed by cisplatin 75 (both on day 1 only) fol lowed by fluorouraci 750 mg/m2 per day as a 24 -hr . I have anti nausea meds that work its just the new chemo is a lot stronger. Men initially treated with Taxotere had favorable outcomes compared to those who were initially treated with Novantrone: Median overall survival was 22 months for men treated with Taxotere first and 15 months for those treated with Novantrone first. Get the latest cancer stories, helpful resources, and personalized advice directly to your inbox. Thinking of you and your family, best wishes. Thank you for sharing your journey and giving me hope. Keep well. All that said, she was down for a mastectomy too, except, the docetaxel absolutely obliterated the cancer. Future - Worst Day (Official Audio) - YouTube 0:00 / 3:06 Future - Worst Day (Official Audio) Future 12.5M subscribers Subscribe 2.5M views 1 year ago #Future #WorstDay Future - Worst. Get comfortable, own the sofa, the remote, get a body pillow, blanket, soft pyjamas, sweets to suck on, films to watch & any other essential supplies! I had 4 months neojuvent you all, besides the sea swimming, crafting, reading and writing poetry, I have taken up cycling result of the biopsy by the end of this week. The ASCO Genitourinary (GU) Cancers Symposium, which ended on February 18, 2023, was a three-day scientific and educational meeting designed to provide attendees with in-depth, multidisciplinary analysis of the timely topics in the study, diagnosis, and treatment of GU malignancies. We can do itnot sure how but we are two thirds there. My tumour is responding well as confirmed by a recent MRI between cycle 3 and 4 so I need to continue to hopefully get through these last two cycles. You may also feel irritable, dizzy, or short of breath. Keep the thoughts positive. Here are six ways to keep your body healthy during chemotherapy treatment: Boost your nutrition. Premedication is required with Docetaxel. (And day 12 after my third and final Tax - I'd probably still say the same. I pushed myself through all the Chemo, the reason, I want to live and if this is the only way then I have to do it. Edema happens when fluid collects under your skin and within the tissues outside your circulatory system. Xx, Thanks Berylynn. diarrhea. Hope we get a good July and August to compensate for the months we missed on the sofa. This may increase the risk of side effects such as nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling . My poor hubby had to give them me.but they hurt and make me have achy legs.plus with the chemo sleepless nights. I got that too. I was on taxotere, carboplatin, and Herceptin every 3 weeks. Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). Does anyone have any suggestions of anything that can help me .. TAXOTERE is sterile, non-pyrogenic, and is available in single-dose vials containing 20 mg (0.5 mL) or 80 mg (2 mL) docetaxel (anhydrous). As horrid as her experience was, it had its payoff. Some of the chemo drugs used to treat prostate cancer include: Docetaxel (Taxotere) Cabazitaxel (Jevtana) Mitoxantrone (Novantrone) Estramustine (Emcyt) In most cases, the first chemo drug given is docetaxel, combined with the steroid drug prednisone. A baking soda and/or salt with warm water mouth rinse (2 level teaspoons of baking soda or 1 level teaspoon of salt in an eight ounce glass of warm water) is recommended 4 times daily. When thered cell count is low, you may feel tired or weak. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in "floaters." My reaction to Taxol was different. Take care and we will get through this. Take regular Paracetamol and Ibruprofen all day every day. They all worked with the FEC but this new chemo is so much harsher on my mouth. Drink 8-10 glasses of non-alcoholic, un-caffeinated fluid a day to prevent dehydration. I think I am over the worst of the bone aches but the stomach cramps, nausia and erratic bowels throw up a whole new situation. xx, I too had terrible 1st cycle and likewise was admitted due to high temp feel better now but due next cycle on we'd feeling scared I have 3 very young children am incurable breast cancer not sure can cope am now on injection to keep blood count up, Sorry to hear of your experience Jazzy, I know it's not pleasant. So going through the rest of the horror. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. By 2010, the drug had . The mouth issues I suffered with all the way through chemo (didn't have thrush) but would say the mouth part was my worst SE. I feel less guilty doing nothing for a fortnight if others the same sofa days do seem to be extended. In addition, dietary changes may help. I'm fortunate in that my husband is self employed. I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. This chemo certainly throws everything at us to endure. I spent yesterday in A&E with chest pains which turned out to be heartburn and anxiety. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. So my advice is dont be scared to ring the chemo hotline, they know what to advise and whether or not you should go in.. It's horrid and depressing. Do not floss or use toothpicks and use a soft-bristle toothbrush to brush your teeth. It's now a week since my 1st cycle of Docetaxel following 3 cycles of FEC, it has been a dreadful week where the treatment has thrown back every side effect possible. Avoid contact sports and activities that can result in injury or bleeding. I've dealt with everything they have thrown at me with a really positive attitude ( including discussions about possible having to have a double mastectomy due to genetics and a failed pre chemo IVF attempt), but I'm at a loss with what to do with myself at the moment. Let us know how you are all doing xx, Thank you Chrissie2 for your response. If given to a patient whose liver function is abnormal aches have reduced considerably now be his. You may also feel irritable, dizzy, or short of breath slowly... Six ways to keep your body to hold too much and want to rely it... Professionals nor the advice you receive from them thirds there July 1 2010 top of fevers,. 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